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Product Name
T Box Protein 5 Mouse mAb
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Gene ID
6910
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SwissProt ID
Q99593
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Gene Name
TBX5
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Alternative Names
TBX5; T-box transcription factor TBX5; T-box protein 5
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Background
TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 58 kDa; Observed MW: 53 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
7B11
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of TBX5 expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.