产品详情
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Product Name
BLK Mouse mAb
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Gene ID
640
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SwissProt ID
P51451
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Gene Name
BLK
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Alternative Names
BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk
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Background
Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/100-1/200
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Molecular Weight
-
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Clonality
Monoclonal Antibody
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Clonality No.
9D10B7H6; 9D10A8F8
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Isotype
IgG1
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Immunogen
Purified recombinant fragment of BLK expressed in E. Coli.
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Purification
Ascitic Fluid
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Ascitic fluid containing 0.03% sodium azide.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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