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Product Name
TP53(R175H Mutant) Mouse mAb
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SwissProt ID
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Gene Name
TP53(R175H)
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Alternative Names
TP53(R175H)
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Background
TP53 belongs to the p53 proteins family. It is ubiquitously expressed, acts as a tumor suppressor in many tumor types and induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Defects in TP53 are a cause of esophageal cancer (ESCR), lung cancer (LNCR), adrenocortical carcinoma (ADCC), choroid plexus papilloma (CPLPA) and so on.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB,IHC-P,ICC/IF,ELISA
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Dilution Ratio
WB:1/1000-1/5000;IHC-P: 1/50-1/100;ELISA: 1/1000-1/5000
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Clonality
Monoclonal Antibody
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Clonality No.
2O5-X5-J5
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Isotype
IgG2b
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Immunogen
A synthetic peptide from the internal region of TP53 which includes the mutation of R175H, human origin
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing