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Product Name
RET(C634Y Mutant) Mouse mAb
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SwissProt ID
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Gene Name
RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B
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Alternative Names
RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B
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Background
RET protein is encoded by the RET proto- oncogene. It is a receptor tyrosine kinase. RET loss of function mutations are associated with the development of Hirschsprung’s disease, while gain of function mutations are associated with development of various types of human cancer, including medullary thyroid carcinoma, multiple endocrine neoplasia type 2A and 2B, pheochromocytoma and parathyroid hyperplasia.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB, IHC-P,ELISA
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Dilution Ratio
ELISA: 1/1000-1/2000 WB: 1/500-1/1000 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
6E1-Q5-W6
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of RET which includes the mutation of C634Y, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing