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Product Name
PIK3CA(E545K Mutant) Rabbit pAb
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SwissProt ID
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Gene Name
PtdIns-3-kinase subunit p110-alpha; p110alpha;Phosphoinositide 3-kinase alpha
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Alternative Names
PtdIns-3-kinase subunit p110-alpha; p110alpha;Phosphoinositide 3-kinase alpha
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Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2. The PIK3CA gene is one of the most frequently mutated genes in human cancers.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Vertebrates
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Application
WB,IHC-P,IP,ELISA
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Dilution Ratio
WB:1/100-1/1000; IHC-P: 1/10-1/100; ELISA: 1/100-1/5000
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Clonality
Polyclonal Antibody
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Clonality No.
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of PIK3CA(E545K) of human origin.
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Purification
Purified from serum
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing