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Product Name
BRaf(V600M Mutant) Mouse mAb
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SwissProt ID
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Gene Name
BRAF,BRAF1,RAFB1
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Alternative Names
BRAF,BRAF1,RAFB1
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Background
BRAF belongs to a family of serine-threonine protein kinases. As a part of a signaling pathway known as the the RAS/MAPK pathway, it plays an important part in many cellular processes. The processes include cell proliferation, differentiation and transcriptional regulation. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been found in cancers.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
IHC-P, ICC/IF, ELISA
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Dilution Ratio
ELISA: 1/1000-1/5000 ICC/IF: 1/50-1/100 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
5L2-K6-A1
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of BRAF which includes the mutation of V600M, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing