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Product Name
BRCA1(C61G Mutant) Mouse mAb
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SwissProt ID
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Gene Name
BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP
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Alternative Names
BRCA1, BRCC1, IRIS, PNCA4, PPP1R53, PSCP
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Background
BRCA1 is normally expressed in cells of breast and other tissues, where it helps repair damaged DNA or destroy cells if DNA cannot be repaired. It is involved in the repair of chromosomal damage with an important role in the error-free repair of DNA double-strand breaks. If BRCA1 itself is damaged by a BRCA1 mutation, damaged DNA is not repaired properly, and this increases the risk for breast cancer.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB, IHC-P,ELISA
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Dilution Ratio
ELISA: 1/1000-1/2000,WB: 1/500-1/1000,IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
6N9-Y3-D8
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of BRCA1 which includes the mutation of C61G, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing