产品详情
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Product Name
BRaf(N581S Mutant) Mouse mAb
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SwissProt ID
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Gene Name
BRAF, BRAF1, RAFB1
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Alternative Names
BRAF, BRAF1, RAFB1
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Background
B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in BRAF have been found in cancers.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB, IHC-P, IP,ELISA
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Dilution Ratio
ELISA: 1/1000-1/5000 WB: 1/500-1/2000 IHC-P: 1/100-200
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Clonality
Monoclonal Antibody
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Clonality No.
6R3-Y9-N3
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Immunogen
A synthetic peptide from the internal region of Braf (N581S), human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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