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Product Name
AKT1(E49K Mutant) Mouse mAb
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SwissProt ID
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Gene Name
AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
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Alternative Names
AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA
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Background
AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinases, which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Its function is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. There are evidences that mutation or abnormal expression in AKT1 is associated with cancers.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Vertebrates
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Application
WB, IHC-P,ELISA
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Dilution Ratio
ELISA: 1/1000-1/5000 WB: 1/500-1/2000 IHC-P: 1/50-1/100
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Clonality
Monoclonal Antibody
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Clonality No.
9C7-M4-B3
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Isotype
IgG
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Immunogen
A synthetic peptide from the internal region of AKT1 which includes the mutation of E49K, human origin.
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Purification
Purified from ascites
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
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Storage
Store at -20°C. Avoid repeated freezing and thawing