产品详情
-
Product Name
Arginase 2 Mouse mAb
-
Gene ID
384
-
SwissProt ID
P78540
-
Gene Name
ARG2
-
Alternative Names
ARG2
-
Background
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4+ and CD8+ T cells. May suppress inflammation-related signaling in asthmatic airway epithelium. May contribute to the immune evasion of H.pylori by restricting M1 macrophage activation and polyamine metabolism. In fetal dendritic cells may play a role in promoting immune suppression and T cell TNF-alpha production during gestation. Regulates RPS6KB1 signaling, which promotes endothelial cell senescence and inflammation and implicates NOS3/eNOS dysfunction.
-
Research Field
Metabolomics
-
Product Categories
Primary antibody
-
Host
Mouse
-
Reactivity
Mouse,Rat
-
Application
WB
-
Dilution Ratio
WB:1/500-1/1000
-
Molecular Weight
Calculated MW: 40 kDa; Observed MW:40 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
9Q7-M1-N7
-
Isotype
IgG1/kappa
-
Immunogen
Peptide
-
Purification
Protein G
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in PBS, Glycerol and BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。