产品详情
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Product Name
ALDH5A1 Mouse mAb
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Gene ID
7915
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SwissProt ID
P51649
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Gene Name
ALDH5A1
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Alternative Names
SSADH
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Background
Succinate-semialdehyde dehydrogenase is an enzyme that in humans is encoded by the ALDH5A1 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD+-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter γ-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Mouse
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB：1/500-1/1000 IHC-P：1/50-1/100
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Molecular Weight
Calculated MW: 51 kDa; Observed MW:51 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
1R8-G4-V2
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Isotype
IgG1/Kappa
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Immunogen
Peptide
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Purification
Protein G
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS, Glycerol and BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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