产品详情
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Product Name
APC Rat mAb
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Gene ID
11789
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SwissProt ID
Q61315
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Gene Name
Apc
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Alternative Names
APC; Adenomatous polyposis coli protein; Protein APC; mAPC
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Background
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration (By similarity).
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Research Field
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Product Categories
Primary antibody
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Host
Rat
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Reactivity
Mouse
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 311 kDa; Observed MW: 311 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
13F7
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Isotype
IgG2a
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Immunogen
APC protein containing region A shown above
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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