产品详情
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Product Name
BORIS Rat mAb
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Gene ID
664799
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SwissProt ID
A2APF3
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Gene Name
Ctcfl
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Alternative Names
Boris; Brother of the regulator of imprinted sites; CCCTC-binding factor; CTCF paralog; CTCF-like protein
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Background
Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2.
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Research Field
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Product Categories
Primary antibody
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Host
Rat
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Reactivity
Mouse
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 73 kDa; Observed MW: 73 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
2E5
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Isotype
IgG2a
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Immunogen
Recombinant mouse BORIS
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 0.09% sodium azide as a preservative.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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