产品详情
-
Product Name
Munc 13-4 Rabbit mAb
-
Gene ID
201294
-
SwissProt ID
Q70J99
-
Gene Name
UNC13D
-
Alternative Names
Munc13-4,Protein unc-13 homolog D
-
Background
Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca2+-dependent secretory lysosome exocytosis in mast cells.
-
Research Field
Immunology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human, Mouse
-
Application
WB,FC
-
Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
-
Molecular Weight
Calculated MW:123 kDa;Observed MW: 123 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R07-3X-1
-
Isotype
IgG
-
Immunogen
Peptide
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用,请参照上方的缩写含义,仔细对照后选择合适的产品。