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Product Name
Growth Hormone Receptor Rabbit mAb
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Gene ID
2690
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SwissProt ID
P10912
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Gene Name
GHR
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Alternative Names
GHR; Growth hormone receptor; GH receptor; Somatotropin receptor
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Background
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
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Research Field
Signal Transduction
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Product Categories
Recombinant Rabbit Monoclonal antibody
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Host
Rabbit
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Reactivity
Rat
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 72 kDa; Observed MW: 120 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-6E6
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Isotype
IgG
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Immunogen
A synthetic peptide of human Growth hormone receptor
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.