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Product Name
VCAM1 Rabbit mAb
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Gene ID
22329
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SwissProt ID
P29533
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Gene Name
Vcam1
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Alternative Names
VCAM1; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106
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Background
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse
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Application
WB,IP
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Cited
WB (Human)
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 81 kDa; Observed MW: 100 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-6E9
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Isotype
IgG
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Immunogen
Recombinant protein of mouse VCAM1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.