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Product Name
CDT2 Rabbit mAb
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Gene ID
51514
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SwissProt ID
Q9NZJ0
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Gene Name
DTL
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Alternative Names
CDW1; DCAF2; Dtl; L2DTL; RAMP
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Background
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 79 kDa; Observed MW: 79 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-2G4
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Isotype
IgG
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Immunogen
Recombinant protein of human CDT2
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.