-
Product Name
Rac3 Rabbit mAb
-
Gene ID
5881
-
SwissProt ID
P60763
-
Gene Name
RAC3
-
Alternative Names
ras-related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac3)
-
Background
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IHC-P
-
Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
-
Molecular Weight
Calculated MW: 21 kDa; Observed MW: 21 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R01-6I8
-
Isotype
IgG
-
Immunogen
A synthetic peptide of human RAC3
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.