产品详情
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Product Name
CD55 Rabbit mAb
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Gene ID
1604
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SwissProt ID
P08174
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Gene Name
CD55
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Alternative Names
CD55; CR; DAF; Complement decay-accelerating factor; CD55
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Background
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 41 kDa; Observed MW: 78 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-7H4
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Isotype
IgG
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Immunogen
A synthetic peptide of human CD55
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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