-
Product Name
MLH1 Rabbit mAb
-
Gene ID
4292
-
SwissProt ID
P40692
-
Gene Name
MLH1
-
Alternative Names
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
-
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Rat
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 85 kDa; Observed MW: 85 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R05-1G4
-
Isotype
IgG
-
Immunogen
A synthetic peptide of human MLH1
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.