-
Product Name
FOXA1 Rabbit mAb
-
Gene ID
3169
-
SwissProt ID
P55317
-
Gene Name
FOXA1
-
Alternative Names
FOXA1; Forkhead box A1; Forkhead box protein A1; HNF-3-alpha; TCF3A; HNF3A; Transcription factor 3A
-
Background
Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Rat
-
Application
WB,ICC/IF
-
Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
-
Molecular Weight
Calculated MW: 49 kDa; Observed MW: 49 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R04-5A7
-
Isotype
IgG
-
Immunogen
Recombinant protein of human FOXA1
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.