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Product Name
Phospho-Cannabinoid Receptor I (Ser316) Rabbit mAb
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Gene ID
1268
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SwissProt ID
P21554
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Gene Name
CNR1
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Alternative Names
CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6
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Background
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 53 kDa; Observed MW: 53 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-9A1
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Isotype
IgG
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Ser316 of human Cannabinoid Receptor I
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Phosphorylated
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.