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货号： R24756

别名： IRF1; Interferon regulatory factor 1; IRF-1

应用： WB,IHC-F,IHC-P,ICC/IF,IP

反应种属： Human,Mouse,Rat

目录价格：

RMB(含税报价)

数量： - + （库存件）

查看代理商预计货期：现货说明书PDF

产品详情

Product Name

IRF1 Rabbit mAb
Gene ID

3659
SwissProt ID

P10914
Gene Name

IRF1
Alternative Names

IRF1; Interferon regulatory factor 1; IRF-1
Background

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.
Research Field

Epigenetics and Nuclear Signaling
Product Categories

Primary antibody
Host

Rabbit
Reactivity

Human,Mouse,Rat
Application

WB,IHC-F,IHC-P,ICC/IF,IP
Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Molecular Weight

Calculated MW: 37 kDa; Observed MW: 48 kDa
Clonality

Monoclonal Antibody
Clonality No.

R08-1B4
Isotype

IgG
Immunogen

Recombinant protein of human IRF1
Purification

Affinity Purified
Conjugation

Unconjugated
Modification

Unmodified
Form

Liquid
Buffer System

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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应用缩写

WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定正能生物产品售后保障范围仅限官网产品详情页中“应用”一栏写明的实验应用，请参照上方的缩写含义，仔细对照后选择合适的产品。

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