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Product Name
PCBP2 Rabbit mAb
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Gene ID
5094
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SwissProt ID
Q15366
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Gene Name
PCBP2
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Alternative Names
HNRPE2; HNRNPE2; hnRNP-E2
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Background
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509). It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509).
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Research Field
Microbiology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Mouse,Rat
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Application
WB,IP
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Dilution Ratio
WB: 1/500-1/1000 IP: 1/20
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Molecular Weight
Calculated MW: 39 kDa; Observed MW: 35-45 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-2F5
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Isotype
IgG
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Immunogen
A synthetic peptide of human PCBP2
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.