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Product Name
Caspase 6 Rabbit mAb
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Gene ID
839
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SwissProt ID
P55212
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Gene Name
CASP6
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Alternative Names
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
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Background
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 33 kDa; Observed MW: 11,33 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-5F9
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Isotype
IgG
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Immunogen
Recombinant protein of human Caspase-6
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.