-
Product Name
DOK1 Rabbit mAb
-
Gene ID
1796
-
SwissProt ID
Q99704
-
Gene Name
DOK1
-
Alternative Names
DOK1; Docking protein 1; Downstream of tyrosine kinase 1; p62(dok); pp62
-
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
-
Research Field
Signal Transduction
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,ICC/IF
-
Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
-
Molecular Weight
Calculated MW: 52 kDa; Observed MW: 65 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R04-2Y2
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human DOK1
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.