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Product Name
DOCK2 Rabbit mAb
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Gene ID
1794
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SwissProt ID
Q92608
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Gene Name
DOCK2
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Alternative Names
DOCK 2; IMD40
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Background
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 212 kDa; Observed MW: 212 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-1V5
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human DOCK2
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.