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Product Name
LSP1 Rabbit mAb
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Gene ID
4046
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SwissProt ID
P33241
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Gene Name
LSP1
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Alternative Names
Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein
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Background
LSP1 is a 52 kDa leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its C-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion. LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 37 kDa; Observed MW: 52 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-7G2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human LSP1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.