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Product Name
GRK2 Rabbit mAb
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Gene ID
156
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SwissProt ID
P25098
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Gene Name
GRK2
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Alternative Names
GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1
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Background
GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 80 kDa; Observed MW: 80 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-1J7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human GRK2
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.