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Product Name
LIN28B Rabbit mAb
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Gene ID
389421
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SwissProt ID
Q6ZN17
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Gene Name
LIN28B
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Alternative Names
CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B
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Background
It has recently been shown that upregulation of LIN28A and LIN28B in primary human tumors and human cancer cell lines is correlated with downregulation of let-7 miRNAs. LIN28 genes are reported to be involved in primordial germ cell development and germ cell malignancy. In addition, allelic variation in LIN28B is associated with regulating the timing of puberty in humans.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF,FC,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 27 kDa; Observed MW: 30 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R05-7F1
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Lin28B
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.