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Product Name
PIM2 Rabbit mAb
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Gene ID
11040
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SwissProt ID
Q9P1W9
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Gene Name
PIM2
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Alternative Names
PIM2; Serine/threonine-protein kinase pim-2; Pim-2h
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Background
Promotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappaB kinase/NF-kappaB cascade; this process requires phosphorylation of MAP3K8/COT. Prevents apoptosis induced by growth factor withdrawal via inhibition of caspase-3 activation, and via phosphorylation of pro-apoptotic proteins.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50
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Molecular Weight
Calculated MW: 34 kDa; Observed MW: 37 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-8B6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human PIM2
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.