产品详情
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Product Name
KMT4 Rabbit mAb
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Gene ID
84444
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SwissProt ID
Q8TEK3
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Gene Name
DOT1L
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Alternative Names
DOT 1; DOT1L; KMT4; Histone methyltransferase DOT1L; H3 lysine-79 specific
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Background
Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 165 kDa; Observed MW: 185 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-1G7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human KMT4 / Dot1L
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
应用缩写
WB:蛋白质印迹法IHC-P:石蜡切片样本的免疫组织化学法IHC-F:冰冻切片样本的免疫组织化学法ICC/IF:免疫细胞荧光 IP:免疫沉淀法FC:流式细胞术ChIP:染色质免疫沉淀法ELISA:酶联免疫吸附测定
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