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Product Name
Insulin Degrading Enzyme Rabbit mAb
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Gene ID
3416
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SwissProt ID
P14735
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Gene Name
IDE
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Alternative Names
INSULYSIN; Insulin degrading enzyme; IDE
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Background
This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200
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Molecular Weight
Calculated MW: 118 kDa; Observed MW: 118 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-4E8
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Isotype
IgG
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Immunogen
A synthetic peptide of human Insulin degrading enzyme/IDE
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.