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Product Name
IKZF3 Rabbit mAb
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Gene ID
22806
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SwissProt ID
Q9UKT9
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Gene Name
IKZF3
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Alternative Names
IKZF3; ZNFN1A3; Zinc finger protein Aiolos; Ikaros family zinc finger protein 3
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Background
Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 58 kDa; Observed MW: 58 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-0C5
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Isotype
IgG
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Immunogen
A synthetic peptide of human IKZF3
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.