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Product Name
SMCHD1 Rabbit mAb
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Gene ID
23347
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SwissProt ID
A6NHR9
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Gene Name
SMCHD1
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Alternative Names
BAMS; FSHD2; Smchd1
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Background
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 226 kDa; Observed MW: 226 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-7N6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human SMCHD1
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.