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Product Name
p53 Rabbit mAb
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Gene ID
7157
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SwissProt ID
P04637
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Gene Name
TP53
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Alternative Names
TP53; P53; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
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Background
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.
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Research Field
Cell Biology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF,FC,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 44 kDa; Observed MW: 53 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R09-5E6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human p53
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.