-
Product Name
Dnmt3a Rabbit mAb
-
Gene ID
1788
-
SwissProt ID
Q9Y6K1
-
Gene Name
DNMT3A
-
Alternative Names
DNMT3A2; M.HsaIIIA; Dnmt3a; MCMT; DNA methyltransferase 3a
-
Background
Methylation of DNA at cytosine residues in mammalian cells is a heritable, epigenetic modification that is critical for proper regulation of gene expression, genomic imprinting and development. Three families of mammalian DNA methyltransferases have been identified: DNMT1, DNMT2 and DNMT3. DNMT1 is constitutively expressed in proliferating cells and functions as a maintenance methyltransferase, transferring proper methylation patterns to newly synthesized DNA during replication.
-
Research Field
Epigenetics and Nuclear Signaling
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 102 kDa; Observed MW: 130 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R03-8H4
-
Isotype
IgG
-
Immunogen
A synthetic peptide of human Dnmt3a
-
Purification
Affinity Purified
-
Conjugation
Unconjugated
-
Modification
Unmodified
-
Form
Liquid
-
Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.