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Product Name
MYL2 Rabbit mAb
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Gene ID
4633
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SwissProt ID
P10916
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Gene Name
MYL2
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Alternative Names
Myosin regulatory light chain 2; ventricular/cardiac muscle isoform; MLC-2; MLC-2v
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Background
Myosin is composed of six polypeptide chains: two identical heavy chains and two pairs of light chains. Myosin light chain 2 (MLC2), also known as myosin regulatory light chain (MRLC), RLC, or LC20, has many isoforms depending on its distribution. In smooth muscle, MLC2 is phosphorylated at Thr18 and Ser19 by myosin light chain kinase (MLCK) in a Ca2+/calmodulin-dependent manner.
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Research Field
Signal Transduction
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/50
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Molecular Weight
Calculated MW: 19 kDa; Observed MW: 19 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R08-2D2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human Myosin Light Chain 2
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.