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Product Name
DKK1 Rabbit mAb
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Gene ID
22943
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SwissProt ID
O94907
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Gene Name
DKK1
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Alternative Names
DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK
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Background
DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB,IHC-P,ICC/IF,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 29 kDa; Observed MW: 38 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-6J6
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human DKK1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.