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Product Name
E2F2 Rabbit mAb
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Gene ID
1870
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SwissProt ID
Q14209
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Gene Name
E2F2
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Alternative Names
De2f2; E2F transcription factor 2; E2F-2; Transcription factor E2F2
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Background
Play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,FC
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Dilution Ratio
WB: 1/500-1/1000 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 48 kDa; Observed MW: 48 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R03-6G9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human E2F2
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.