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Product Name
ERK5 Rabbit mAb
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Gene ID
5598
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SwissProt ID
Q13164
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Gene Name
MAPK7
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Alternative Names
Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; ERK 4; ERK 5; ERK-5; ERK4; ERK5; MAP kinase 7; MAPK 7; Mitogen Activated Protein Kinase
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Background
Erk5 (Mitogen-activated protein kinase 7, Big mitogen-activated protein kinase 1) is a member of the MAPK superfamily implicated in the regulation numerous cellular processes including proliferation, differentiation, and survival. In neuronal cells, Erk5 is required for NGF-induced neurite outgrowth, neuronal homeostasis, and survival. Erk5 is thought to play a role in blood vessel integrity via maintenance of endothelial cell migration and barrier function.
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,ICC/IF,FC,IP
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/50 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 88 kDa; Observed MW: 115 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-9G1
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human ERK5
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.