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Product Name
PAX6 Rabbit mAb
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Gene ID
5080
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SwissProt ID
P26367
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Gene Name
PAX6
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Alternative Names
PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin
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Background
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity).
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Research Field
Neuroscience
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Mouse,Rat
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Application
WB,IHC-P,FC
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 47 kDa; Observed MW: 47 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R07-7D2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human PAX6
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.