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Product Name
RNase L Rabbit mAb
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Gene ID
6041
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SwissProt ID
Q05823
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Gene Name
RNASEL
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Alternative Names
PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4
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Background
Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB
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Dilution Ratio
WB: 1/500-1/1000
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Molecular Weight
Calculated MW: 84 kDa; Observed MW: 80 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-2P2
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human RNase L
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.