-
Product Name
Phospho-AKT1 (Ser124) Rabbit mAb
-
Gene ID
207
-
SwissProt ID
P31749
-
Gene Name
AKT1
-
Alternative Names
AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
-
Background
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
-
Research Field
Signal Transduction
-
Product Categories
Recombinant Rabbit Monoclonal antibody
-
Host
Rabbit
-
Reactivity
Human,Mouse,Rat
-
Application
WB,IP
-
Dilution Ratio
WB: 1/500-1/1000 IP: 1/50
-
Molecular Weight
Calculated MW: 56 kDa; Observed MW: 60 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R04-4X5
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human AKT1
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Phosphorylated
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.