-
Product Name
Phospho-Rac1/CDC42 (Ser71) Rabbit mAb
-
Gene ID
998/5879
-
SwissProt ID
P60953/P63000
-
Gene Name
CDC42/RAC1
-
Alternative Names
CDC42; CDC42Hs; G25K; TKS; MIG5; Ras like protein TC25
-
Background
Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.
-
Research Field
Cell Biology
-
Product Categories
Primary antibody
-
Host
Rabbit
-
Reactivity
Human
-
Application
WB
-
Dilution Ratio
WB: 1/500-1/1000
-
Molecular Weight
Calculated MW: 21 kDa; Observed MW: 24 kDa
-
Clonality
Monoclonal Antibody
-
Clonality No.
R09-6M1
-
Isotype
IgG
-
Immunogen
A synthesized peptide derived from human Phospho-Rac1/Cdc42 (Ser71)
-
Purification
Affinity Chromatography
-
Conjugation
Unconjugated
-
Modification
Phosphorylated
-
Form
Liquid
-
Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.