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Product Name
Sialoadhesin/CD169 Rabbit mAb
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Gene ID
6614
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SwissProt ID
Q9BZZ2
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Gene Name
SIGLEC1
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Alternative Names
SIGLEC1;SN;Sialoadhesin;Sialic acid-binding Ig-like lectin 1 (Siglec-1);CD169
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Background
Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response (PubMed:12940982, PubMed:33489013).
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
IHC-P
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Dilution Ratio
IHC: 1/100-1/200
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Clonality
Monoclonal Antibody
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Clonality No.
R09-1X-3
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human CD169
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.