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Product Name
Toll-Like Receptor 7 Rabbit mAb
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Gene ID
51284
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SwissProt ID
Q9NYK1
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Gene Name
TLR7
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Alternative Names
Toll-Like Receptor 7; PRO285; TLR 7; Tlr7; Toll like receptor 7; UNQ248
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Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
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Research Field
Immunology
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100
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Molecular Weight
Calculated MW: 121 kDa; Observed MW: 140 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-8B8
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human TLR7
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.