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Product Name
MCM7 Rabbit mAb
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Gene ID
4176
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SwissProt ID
P33993
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Gene Name
MCM7
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Alternative Names
MCM7; CDC47; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; P1.1-MCM3
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Background
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,ICC/IF,FC
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Dilution Ratio
WB: 1/500-1/1000 IF: 1/50-1/200 FC: 1/50-1/100
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Molecular Weight
Calculated MW: 81 kDa; Observed MW: 81 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R04-1J7
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human MCM7
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.