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Product Name
MBD1 Rabbit mAb
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Gene ID
4152
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SwissProt ID
Q9UIS9
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Gene Name
MBD1
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Alternative Names
CXXC 3; Mbd1; MECP1 COMPLEX; PCM1; RFT
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Background
Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS).
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human
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Application
WB,IHC-P,ICC/IF,IP
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
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Molecular Weight
Calculated MW: 67 kDa; Observed MW: 67 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R02-7E9
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Isotype
IgG
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Immunogen
A synthesized peptide derived from human MBD1
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Purification
Affinity Chromatography
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Conjugation
Unconjugated
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Modification
Unmodified
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Form
Liquid
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Buffer System
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.