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Product Name
TriMethyl-Histone H3 (Lys27) Rabbit mAb
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Gene ID
8350
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SwissProt ID
P68431
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Gene Name
H3C1
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Alternative Names
H3K27me3; H3 histone; HIST1H3A; Histone cluster 1; H3a
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Background
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
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Research Field
Epigenetics and Nuclear Signaling
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Product Categories
Primary antibody
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Host
Rabbit
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Reactivity
Human,Rat
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Application
WB,IHC-F,IHC-P,ICC/IF,IP,ChIP
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Cited
IF (Mouse)
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Dilution Ratio
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 ChIP: 1/20
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Molecular Weight
Calculated MW: 15 kDa; Observed MW: 15 kDa
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Clonality
Monoclonal Antibody
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Clonality No.
R01-8I4
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Isotype
IgG
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Immunogen
A synthetic methyl-peptide corresponding to residues surrounding Lys27 of human Histone H3
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Purification
Affinity Purified
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Conjugation
Unconjugated
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Modification
Methylated
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Form
Liquid
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Buffer System
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.